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目的:探讨不同时间长度的热暴露对大鼠体温、体重及应激器官重量的影响及枸杞多糖的干预作用。方法:选用雄性Wistar大鼠,随机分为对照组、热暴露组及热暴露+枸杞多糖组。对照组:置于室温24℃的环境中;热暴露组与热暴露+枸杞多糖组:环境温度为32℃,分别进行7、14、35天的热暴露;采用体温遥感技术监测大鼠体温变化,并摘取其脑垂体及肾上腺等器官为实验标本。结果:不同时间长度的热暴露各组对大鼠的体温和体重均无影响;7天热暴露可增加大鼠脑垂体和肾上腺的相对重量,而14和35天的热暴露对大鼠脑垂体及肾上腺的相对重量无影响。结论:长时间的热暴露可使机体产生热适应,枸杞多糖对急性热应激引起的应激器官相对重量的增加无缓解作用。
OBJECTIVE: To investigate the effects of different time exposures on body temperature, body weight and organ weight in rats and the intervention of LBP. Methods: Male Wistar rats were randomly divided into control group, heat exposure group and heat exposure + LBP group. Control group: placed in the environment of 24 ℃ at room temperature; Heat exposure group and heat exposure + LBP group: the ambient temperature was 32 ℃, respectively, 7, 14, 35 days of heat exposure; body temperature using remote sensing to monitor changes in body temperature , And picked its pituitary and adrenal and other organs as experimental specimens. RESULTS: Heat exposure for different lengths of time had no effect on body temperature and body weight in rats; heat exposure for 7 days increased the relative weight of pituitary and adrenal in rats, while heat exposure on days 14 and 35 did not affect rat pituitary And the relative weight of the adrenal no effect. CONCLUSION: Prolonged heat exposure can make the body produce heat adaptation. Lycium barbarum polysaccharide has no relieving effect on the increase of relative weight of stress-induced organs caused by acute heat stress.