论文部分内容阅读
目的丙泊酚不同配伍在无痛肠镜检查中的效应。方法60例门诊肠镜检查病人,随机分为三组,每组20例,Ⅰ组为丙泊酚组,Ⅱ组芬太尼+丙泊酚组,Ⅲ组为氯胺酮+芬太尼+丙泊酚组,分别记录用药前、后2min及检查结束时的HR、MAP、SpO2,并观察丙泊酚的用量及其麻醉效果。结果Ⅰ组、Ⅱ组病人用药后2minHR下降但无统计学意义(P>0.05).Ⅰ组病人用药后2minMAP下降明显,与用药前比较具有显著差异(P<0.01);Ⅱ组病人用药后2minMAP下降,与用药前比较有差异(P<0.05),Ⅰ组病人用药后2minSpO2下降明显与用药前比较具有显著差异(P<0.01)。Ⅱ组、Ⅲ组丙泊酚用量明显减少(P<0.01),Ⅱ组、Ⅲ组麻醉效果优于Ⅰ组(P<0.05)。结论Ⅲ组麻醉效果显著,对循环呼吸影响较小,可安全用于门诊无痛肠镜检查。
Objective To investigate the effect of propofol compatibility on painless colonoscopy. Methods Sixty patients with enteroscopy were randomly divided into three groups (20 in each group), group Ⅰ was propofol group, group Ⅱ was fentanyl + propofol group, group Ⅲ was ketamine + fentanyl + Phenol group were recorded before treatment, 2min after the end of the test and HR, MAP, SpO2, and to observe the amount of propofol and its anesthetic effect. Results The HRR of patients in group I and group II decreased at 2min after treatment, but there was no statistical significance (P> 0.05) .MAP in patients in group I decreased significantly at 2min after drug administration, with significant difference compared with that before treatment (P <0.01) (P <0.05). The decrease of SpO2 in group I was significantly lower than that before treatment (P <0.01). The dosage of propofol in group Ⅱ and group Ⅲ decreased significantly (P <0.01). The anesthesia in group Ⅱ and group Ⅲ was better than that of group Ⅰ (P <0.05). Conclusion The effect of anesthesia in group Ⅲ is remarkable and has little effect on circulatory respiration. It can be safely used in outpatient painless colonoscopy.