论文部分内容阅读
据报道钙通道阻滞剂可用于具有正常眼压的青光眼,作用机制不完全清楚。很多研究表明,应用钙通道阻滞剂后,可使眼部血流增加。因为在开角型青光眼和正常眼压的青光眼患者,眼部动脉和视神经头微循环血流速度减慢,所以,钙通道阻滞剂增加眼部血流的作用可能是其治疗青光眼的机制。另外,更新的研究表明内皮素—1(ET—1)与正常眼压青光眼的发病有关,ET—1可使病人眼部血
It is reported that calcium channel blockers can be used for glaucoma with normal intraocular pressure, the mechanism of action is not completely clear. Many studies have shown that the application of calcium channel blockers, can make eye blood flow increased. Because glaucoma in open-angle glaucoma and normal intraocular pressure causes a slowing of the blood flow in the ocular arteries and optic nerve microcirculation, the effect of calcium channel blockers on ocular blood flow may be its mechanism for the treatment of glaucoma. In addition, more recent studies have shown that ET-1 is associated with the development of normal intraocular pressure glaucoma. ET-1 can cause ocular blood in patients