Restraint stress induces and exacerbates intestinalinflammation in interleukin-10 deficient mice

• 作 者: Seong-Joon Koh Ji Won Kim By
• 机 构: Seong-JoonKoh,JooSungKim
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2015年28期
• 关键词: STRESS COLITIS INTERLEUKIN-10 Inflammatorybowel DISEASE MOUSE MODEL StressColiti
• 基金项目: Supported by SNUH Research Fund,No.06-2011-1770,Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education,No.NRF-2014R1A1A2057695

AIM To investigate the effects of restraint stress onchronic colitis in interleukin （IL）-10 deficient （IL-10-/-）mice.METHODS： The first experiment compared the effectof restraint stress on the development of intestinalinflammation in wild-type and IL-10-/