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目的:探讨间质性肺炎临床治疗方法。方法:选择4例间质性肺炎并发严重肺动脉高压(mPAP>40mmHg)的病人,其中2例患者均静脉注射前列环素治疗,而引起低氧血症。结果:静脉注射前列环素治疗,短暂临床症状减轻以后,病人的呼吸困难逐渐加重,2例病人在1年左右死亡,2例在治疗后5年内死亡。结论:间质性肺炎继发肺动脉高压临床恶性程度高,应尽早治疗,延长患者生存时间。
Objective: To explore the clinical treatment of interstitial pneumonia. METHODS: Four patients with interstitial pneumonia complicated with severe pulmonary hypertension (mPAP> 40 mmHg) were enrolled. Two of them were treated with prostacyclin intravenously, causing hypoxemia. RESULTS: After intravenous prostacyclin treatment, the patient’s dyspnea was gradually aggravated after a brief clinical symptom relief. Two patients died within one year and two patients died within five years after treatment. Conclusion: The clinical severity of pulmonary hypertension secondary to interstitial pneumonia should be treated as soon as possible to prolong the survival time of patients.