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目的分析热性惊厥患儿肠道感染常见的病毒,探讨肠道病毒感染与热性惊厥的相关性。方法选择热性惊厥患者81例为研究对象。采集患儿的粪便,用胶体金法进行轮状病毒和肠腺病毒的检测,用PCR法进行诺如病毒和星状病毒的检测,分析病毒感染后的临床特征。比较各种肠道病毒在单纯热性惊厥和复杂热性惊厥的感染比例。结果 4种肠道病毒中,热性惊厥患儿轮状病毒的感染比例最高,且轮状病毒的感染比例在单纯热性惊厥组和复杂性热性惊厥之间存在统计学差异(P<0.05)。未发现其他3种病毒在两组之间的差异(P>0.05)。结论单纯热性惊厥组患儿更容易合并轮状病毒的感染。我们应注意热性惊厥患儿肠道病毒的检测。
Objective To analyze the common viruses of enteric infections in children with febrile seizures and to explore the correlation between enteroviral infection and febrile seizures. Methods 81 cases of febrile seizures were selected as the research object. The stools of children were collected, and rotavirus and enteric virus were detected by colloidal gold method. Norovirus and astrovirus were detected by PCR and the clinical features after virus infection were analyzed. Compare the incidence of various enteroviruses in simple febrile seizures and complicated febrile seizures. Results Among the four kinds of enterovirus, the incidence of rotavirus infection in children with febrile seizures was the highest, and the proportion of rotavirus infection in febrile seizures group and complicated febrile seizures was statistically different (P <0.05 ). No other three viruses were found between the two groups (P> 0.05). Conclusions Children with febrile seizures are more likely to have rotavirus infection. We should pay attention to the detection of enteroviruses in children with febrile seizures.