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目的:探讨产前三维超声在胎儿结构畸形筛查中的应用。方法:回顾性分析2015年12月至2016年12月博罗县妇幼保健院收治的孕妇5500例的临床资料,依据产后结果为对照,所有孕妇均给予产前二维、三维超声检查,统计分析所有孕妇的产前超声检查结果、产后胎儿结构畸形情况。结果:产后结果显示,结构畸形胎儿50例(0.91%),二维超声筛查结果显示,结构畸形胎儿49例(0.89%),其敏感度、特异度、准确度为76.00%(38/50)、99.80%(5439/5450)、99.40%(5467/5500),三维超声筛查结果显示,结构畸形胎儿48例(0.87%),其敏感度、特异度、准确度为92.00%(46/50)、99.96%(5448/5450)、99.89%(5494/5500),前者敏感度、特异度、准确度明显低于后者,差异有统计学意义(P<0.05)。结论:产前三维超声检查可有效提高胎儿结构畸形筛查的敏感性、特异性和准确性,可作为一种重要的筛查手段。
Objective: To investigate the application of prenatal three-dimensional ultrasound in fetal structural malformation screening. Methods: The clinical data of 5 500 pregnant women admitted to Boluo Maternal and Child Health Hospital from December 2015 to December 2016 were retrospectively analyzed. All the pregnant women were given prenatal two-dimensional and three-dimensional ultrasonography and statistical analysis Prenatal ultrasound findings of all pregnant women, postpartum fetal structural malformations. Results: Postpartum results showed that there were 50 fetuses (0.91%) with structural deformity and 49 (0.89%) fetuses with structural malformations showed a sensitivity of 76.00% (38/50) ), 99.80% (5439/5450) and 99.40% (5467/5500) respectively. The results of three-dimensional ultrasonography showed that the sensitivity, specificity and accuracy of structural abnormalities in fetus were 48% (0.87% The sensitivity, specificity and accuracy of the former were significantly lower than those of the latter (P <0.05). Conclusion: Prenatal three-dimensional ultrasonography can effectively improve the sensitivity, specificity and accuracy of fetus structural deformity screening as an important screening method.