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目的探讨乌鲁木齐地区维吾尔族人群目前碘营养状况、甲状腺疾病流行情况及碘摄入量与甲状腺疾病的关系。方法对乌鲁木齐地区1 093名维吾尔族成人进行体格检查及问卷调查,测定平均尿碘中位数、甲状腺功能、甲状腺相关抗体,并进行甲状腺B超检查。结果在调查人群中,碘缺乏人数仅占8%,而碘过量人数达到40%,52%的调查对象属于碘适量;平均尿碘中位数(MUI)达(239.50±144.01)μg/L。碘缺乏者TSH水平显著高于碘适量者。不同碘摄入状态人群甲状腺球蛋白抗体(TgAb)阳性率及甲状腺功能异常、甲状腺结节发生率无统计学差别。结论目前乌鲁木齐地区维吾尔族碘缺乏状态已纠正,平均尿碘中位数(MUI)达(239.50±144.01)μg/L。不同碘摄入状态维吾尔族人群甲状腺疾病发病率无明显差别。
Objective To investigate the current status of iodine nutrition, the prevalence of thyroid disease and the relationship between iodine intake and thyroid disease among Uyghur people in Urumqi. Methods A total of 1 093 Uighur adults in Urumqi were investigated by physical examination and questionnaire, mean urinary iodine median, thyroid function and thyroid-related antibodies were measured, and thyroid ultrasound examination was performed. Results Among the surveyed population, the number of iodine deficiency accounted for only 8%, while the number of iodine excess reached 40%. 52% of the respondents belonged to iodine amount; mean urinary iodine median (MUI) was (239.50 ± 144.01) μg / L. TSH levels of iodine deficiency were significantly higher than those of iodine. The thyroid globulin antibody (TgAb) positive rate and thyroid dysfunction in different iodine intake groups, the incidence of thyroid nodules was no significant difference. Conclusions At present, the status of iodine deficiency in Uighur in Urumqi has been corrected. The average urinary iodine median (MUI) reached (239.50 ± 144.01) μg / L. There was no significant difference in the prevalence of thyroid disease between Uyghur and Uygur population under different iodine intake.