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目的:探讨结直肠癌根治术后复发的因素。方法:回顾性查阅2008年1月~2012年12月我院行根治性手术的结直肠癌病人50例,对其临床病理检验情况与预后情况进行分析。结果:复发患者13例,复发率为26.0%,复发中位时间为12.6个月。单因素分析发现原发肿瘤类型、术前血清CEA水平及肿瘤T分期与复发情况有明显相关性(P<0.05),多因素分析发现肿瘤T分期与是结直肠癌复发的独立性相关因素(P<0.05)。结论:结直肠癌根治术后复发率比较高,肿瘤类型、术前血清CEA水平及肿瘤T分期是结直肠癌独立的复发因素,其中T分期是最重要的因素。
Objective: To investigate the recurrence of colorectal cancer after radical surgery factors. Methods: A retrospective review of 50 patients with colorectal cancer undergoing radical surgery in our hospital from January 2008 to December 2012, analyzed the clinicopathological and prognostic factors. Results: Thirteen patients relapsed, the recurrence rate was 26.0%, the median recurrence time was 12.6 months. Univariate analysis showed that primary tumor type, preoperative serum CEA level and tumor T stage were significantly correlated with recurrence (P <0.05). Multivariate analysis showed that tumor T stage was related to the independence of colorectal cancer recurrence P <0.05). Conclusions: The recurrence rate of radical resection of colorectal cancer is relatively high. The type of tumor, serum CEA level and T stage are the independent recurrence factors of colorectal cancer. T stage is the most important factor.