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目的探讨不同程度妊娠高血压综合征患者血清皮质醇水平及与病情严重程度的关系。方法应用化学发光法检测正常孕妇及妊高征患者血清皮质醇含量。结果妊高征孕妇血清皮质醇水平明显高于正常对照组,随着妊高征的病情严重程度的增加,血清皮质醇水平明显增加,各组间血清皮质醇水平均有显著性差异(P<0.05)。结论随着妊高征病情程度的加重,血清皮质醇水平增高;早期检测孕妇血清皮质醇水平,可为妊高征的早期发现和妊高征的病情分期提供临床指导。
Objective To investigate the serum cortisol level in patients with pregnancy induced hypertension and its relationship with the severity of the disease. Methods The levels of serum cortisol in normal pregnant women and patients with pregnancy induced hypertension were detected by chemiluminescence method. Results The serum level of cortisol in pregnant women with PIH was significantly higher than that in the normal control group. Serum cortisol level was significantly increased with the severity of pregnancy-induced hypertension, and serum cortisol levels were significantly different between the groups (P < 0.05). Conclusions With the aggravation of PIH, serum cortisol level is increased. Early detection of serum cortisol level in pregnant women may provide clinical guidance for the early detection of PIH and the stage of PIH.