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目的探讨认知行为治疗对冠心病介入治疗(PCI)术后患者焦虑抑郁和生活质量的影响。方法选择2007年2月~2009年2月在驻马店市第一人民医院心内科接受PCI治疗的全部患者998人,术后1个月进行汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)、对HAMA、HAMD评分分别大于14分和大于17分的患者92人,随机分为两组,每组46人进行干预,研究组在药物治疗的基础上给予规范的认知行为治疗,对照组仅应用抗焦虑、抗抑郁药物,分别在干预前和干预后1个月、3个月和6个月进行HAMA、HAMD、健康状况问卷(SF-36)、艾森克人格问卷(EPQ),最终完成干预的共86例。干预组44例,对照组42例。结果研究组与对照组6个月后SF-36(85.47±16.22vs68.23±10.76,t=5.77)、EPQ评分N因子(44.18±4.13vs53.58±3.08,t=11.90)、HAMA(10.41±3.41vs15.13±4.11,t=5.76)和HAMD(11.43±3.78vs17.89±4.58,t=7.10)评分比较均为P<0.01,差异均有显著性。结论认知行为治疗有助于减轻冠心病介入治疗术后(PCI)患者的焦虑抑郁水平,矫正不良行为,提高PCI患者的生活质量。
Objective To investigate the effect of cognitive behavioral therapy on anxiety, depression and quality of life in patients with coronary artery disease (PCI) after interventional therapy. Methods From February 2007 to February 2009, 998 patients undergoing PCI in Department of Cardiology, First People ’s Hospital of Zhumadian City were enrolled. After one month, Hamilton Anxiety Scale (HAMA), Hamilton Depression Rating Scale (HAMD) , 92 patients with HAMA and HAMD scores greater than 14 and greater than 17 respectively were randomly divided into two groups with 46 in each group for intervention. The study group was given standard cognitive behavioral therapy on the basis of drug treatment and the control group HAMA, HAMD, Health Status Questionnaire (SF-36), Eysenck Personality Questionnaire (EPQ), HAMA, HAMA, Prehypertensive and Antihypertensive drugs were used only before and after 1, 3 and 6 months. A total of 86 cases completed the intervention. Intervention group 44 cases, control group 42 cases. Results After 6 months in the study group and the control group, the scores of SF-36 (85.47 ± 16.22 vs 68.23 ± 10.76, t = 5.77), EPQ score N (44.18 ± 4.13 vs 53.58 ± 3.08, t = 11.90), HAMA ± 3.41vs15.13 ± 4.11, t = 5.76) and HAMD (11.43 ± 3.78vs17.89 ± 4.58, t = 7.10), respectively. All the differences were significant (P <0.01). Conclusions Cognitive behavioral therapy can relieve the anxiety and depression in patients with coronary artery disease after interventional therapy (PCI), correct bad behaviors and improve the quality of life in PCI patients.