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本文作者1980年对山西省太岳山区的10个地方性克汀病(简称克汀病)病区农村作了普查。调查711户,3573人,患病率为6.63％。各调查点地方性甲状腺肿患病率在14.39～28.72％之间,饮水含碘量在1.38±1.29～2.80±7.56μg/L之间,低于国家标准。237例克汀病患者的家庭分布资料作二项分布拟合检验和G检验,均证明克汀病的家庭分布聚集性具有极显著意义(P<0.001)。作者认为,用单一的环境缺碘病因学说颇难解释同一村庄、同一饮水源的人群,有的家庭数人患病,多数家庭无人患病这一现象。并提出,克汀病患者有可能对缺碘敏感的遗传素质。
In 1980, the author made a general survey of 10 endemic cretinism (cretinism) rural areas in Taiyue Mountain of Shanxi Province. A survey of 711 households, 3573 people, the prevalence was 6.63%. The prevalence of endemic goiter in all survey sites ranged from 14.39 to 28.72%, and the iodine content in drinking water ranged from 1.38 ± 1.29 to 2.80 ± 7.56 μg / L, lower than the national standard. Family distribution data of 237 patients with cretinism were used for the bimonthly distribution fitting test and the G test, all of which proved that the distribution of cretinism was highly significant (P <0.001). The author believes that using a single environmental theory of iodine deficiency is difficult to explain the same village, the same drinking water source population, some families sick, most families no one disease. And put forward, cretinism patients may be sensitive to iodine deficiency genetic quality.