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目的分析老年急性ST段抬高型心肌梗死(STEMI)分别置入金属裸支架与药物涂层支架的疗效。方法对2010年6月至2012年11月245例老年急性STEMI行急诊冠状动脉(冠脉)介入治疗的患者,术中随机分别置入金属裸支架(BMS)126例或药物涂层支架(DES)119例,开通梗死罪犯冠脉血管。观察两组2年心血管事件及上消化道出血等情况。结果 BMS组在严重心肌缺血复发、再次心肌梗死、再次靶血管重建、支架内血栓及病死发生率略低于DES组,但差异无统计学意义(P均>0.05)。BMS组上消化道出血率低于DES组(1.6%vs 13.4%,P<0.05)。结论老年急性STEMI急诊冠脉介入治疗患者中,与DES对比,置入BMS未明显降低严重心肌缺血复发率、再次心肌梗死率、再次靶血管重建率、支架内血栓事件,但可明显降低上消化道出血率。
Objective To analyze the curative effect of elderly patients with STEMI treated with bare metal stent and drug-eluting stent. Methods A total of 245 elderly patients with acute STEMI undergoing coronary intervention (coronary intervention) from June 2010 to November 2012 were randomly divided into two groups: BMS (126 cases with bare metal stent) or DES ) 119 cases, opened infarct criminals coronary artery. Two groups of 2-year cardiovascular events and upper gastrointestinal bleeding were observed. Results In BMS group, the incidence of recurrent myocardial infarction and re-target vessel revascularization was significantly lower in BMS group than in DES group, but the difference was not statistically significant (all P> 0.05). The rate of upper gastrointestinal bleeding in BMS group was lower than that in DES group (1.6% vs 13.4%, P <0.05). Conclusions Compared with DES, elderly patients with acute STEMI have no significant reduction in the rate of recurrent myocardial infarction, rate of reinfarcted myocardium, rate of stent thrombosis, but decreased significantly compared with DES Gastrointestinal bleeding rate.