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目的:比较进口硝酸异山梨酯注射液与国产硝酸甘油静脉制剂治疗不稳定性心绞痛的疗效。方法:不稳定性心绞痛病人50例,其中治疗组30例以进口硝酸异山梨酯注射液20mg加入5%葡萄糖液500ml中静脉滴注,qd,连用14d,20例应用硝酸甘油静脉制剂10mg加入5%葡萄糖液500ml中静脉滴注,gd,连用14d作为对照组。结果:治疗组总有效率86.67%,心电图总有效率56.67%,而对照组则分别为75%与40%。组间比较,P值均小于0.05。结论:进口硝酸异山梨酯注射液疗效优于硝酸甘油静脉制剂。
Objective: To compare the efficacy of isosorbide dinitrate injection and domestic nitroglycerin intravenous injection in the treatment of unstable angina pectoris. Methods: Fifty patients with unstable angina pectoris were enrolled in this study. Thirty patients in the treatment group were infused with 20mg of isosorbide dinitrate injection and 500ml of 5% dextrose solution for intravenous infusion for qd for 14 days. Ten patients were given nitroglycerin intravenous injection of 10mg 500ml of glucose solution in intravenous infusion, gd, once every 14d as a control group. Results: The total effective rate was 86.67% in the treatment group and 56.67% in the ECG group, while the control group was 75% and 40% respectively. Between groups, P values were less than 0.05. Conclusion: Isosorbide dinitrate injection is superior to nitroglycerin intravenous injection.