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研究大鼠孕期染锰后对其子代新生鼠血液中微量元素的影响。将妊娠雌性大鼠随机分为 4组 ,腹腔注射氯化锰 ,剂量分别为 0、7.5、15、30 mg/ kg,待其自然分娩后采用原子吸收光谱法测定子代新生鼠血液中微量元素锰、铜、锌和铁含量。实验组与对照组相比 ,实验各组血液内锰含量明显增高 ;锌含量则低于对照组 ;实验各组血液内铜含量与对照组差异无显著性 (P>0 .0 5 ) ;各组间血液内铁含量差异亦无显著性。大鼠孕期染锰 ,使其新生鼠血液中锰、锌等微量元素的含量发生明显变化 ,影响了锰、锌 ,在体内的代谢 ,从而对其子代的生长发育可能产生不利影响。
To study the effects of manganese during pregnancy on trace elements in the blood of newborn offspring of offspring. Pregnant female rats were randomly divided into 4 groups, intraperitoneal injection of manganese chloride, the dose was 0,7.5,15,30 mg / kg, until its natural childbirth after birth by atomic absorption spectrometry Determination of newborn offspring of blood trace elements Manganese, copper, zinc and iron content. Compared with the control group, the content of manganese in the experimental group was significantly higher than that in the control group, while the content of zinc in the experimental group was lower than that in the control group. There was no significant difference between the experimental groups and the control group (P> 0.05) There was no significant difference in iron content between groups. In the third trimester of pregnancy, manganese is impregnated in pregnant rats, which can change the contents of trace elements such as manganese and zinc in the blood of neonatal rats, which may affect the metabolism of manganese and zinc in vivo, which may adversely affect the growth and development of their offspring.