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目的观察宫腔纱条填塞法联合欣母沛治疗中央性前置胎盘产后出血的效果。方法选择2015年1月—2016年10月住院的中央性前置胎盘产后出血产妇68例,随机将所有产妇分为观察组(34例)与对照组(34例)。对照组在胎儿娩出后采用宫腔纱条填塞法止血,观察组在对照组的基础上宫体注射欣母沛。比较两组产后2、24 h出血量,止血时间、手术时间和住院时间,不良反应发生情况。计量资料采用t检验,计数资料采用χ2检验,P<0.05表示差异有统计学意义。结果观察组产后2、24 h的出血量分别为[(294.81±30.54)、(659.41±42.33)ml]明显少于对照组[(527.43±41.12)、(817.25±58.38)ml],比较差异有统计学意义(均P<0.05);观察组止血时间(15.92±3.18)min、手术时间(54.77±6.84)min、住院时间(8.72±1.73)d明显少于对照组[(29.24±3.73)min、(70.43±9.32)min、(13.83±1.91)d],比较差异有统计学意义(均P<0.05)。观察组不良反应总发生率5.88%明显少于对照组20.58%,组间比较差异有统计学意义(P<0.05)。结论对中央性前置胎盘产后出血患者应用宫腔纱条填塞法联合欣母沛治疗,能在短时间内有效止血,减少出血量,手术时间短,利于患者术后恢复,且不良反应少。
Objective To observe the effect of uterine gauze packing combined with Xinmaopei on postpartum hemorrhage in central placenta previa. Methods 68 cases of postpartum hemorrhage in central placenta previa from January 2015 to October 2016 were randomly divided into observation group (34 cases) and control group (34 cases). The control group after the delivery of fetal uterine gauze packing method to stop bleeding, the observation group in the control group based on the body injection of Xin Ma Pei. The bleeding volume, hemostasis time, operation time, hospitalization time and incidence of adverse reactions in both groups were compared at 2, 24 h after delivery. Measurement data using t test, count data using χ2 test, P <0.05 said the difference was statistically significant. Results The amount of bleeding at 2 and 24 hours after delivery in the observation group was significantly lower than that in the control group [(294.81 ± 30.54) vs (659.41 ± 42.33) ml] (527.43 ± 41.12 and (817.25 ± 58.38) ml, respectively (15.92 ± 3.18) min, operation time (54.77 ± 6.84) min and hospitalization time (8.72 ± 1.73) d were significantly lower than those in the control group [(29.24 ± 3.73) min, P <0.05) , (70.43 ± 9.32) min, (13.83 ± 1.91) d, respectively, with significant difference (all P <0.05). The total incidence of adverse reactions in the observation group was significantly lower than that in the control group (5.88% vs 20.58%, P <0.05). Conclusion The application of uterine sliver gauze packing combined with Yanmai Pei treatment in patients with central placenta previa and postpartum hemorrhage can effectively stop bleeding and reduce the amount of bleeding in a short period of time. The operation time is short, which is conducive to the recovery of patients with less adverse reactions.