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目的 初步探讨分次立体定向三维适形放射治疗肝癌伴门静脉癌栓患者的近期疗效。方法 3 1例肝癌伴门静脉癌栓患者应用中科院大恒公司适形系列及 3D治疗计划系统。 10MV -X射线总剂量DT40～ 48GY ,1～ 2个中心 ,70 %～ 90 %等剂量曲线包绕肿瘤边缘。分割方式 :68GY 次 ,3次 周。结果 临床症状改善为 10 0 % ;影像学有效率为 85 .7% ;总生物剂量相同时 ,6GY和 8GY组疗效无差别 ;18例门静脉癌栓全消 ,7例大部分消退 ,3例癌栓略缩小 ,所有患者临床症状得以改善 ,生存期延长。结论 分次立体定向三维适形放射治疗肝癌伴门静脉癌栓患者近期疗效肯定 ,临床值得应用推广
Objective To investigate the short-term curative effect of graded stereotactic three-dimensional conformal radiotherapy for patients with hepatocellular carcinoma and portal vein tumor thrombus. Method 3 1 case of hepatocellular carcinoma with portal vein tumor thrombus application Daheng company of Chinese Academy of Sciences conformal series and 3D treatment planning system. 10MV-X-ray total dose of DT40 ~ 48GY, 1 to 2 centers, 70% to 90% isodose curve wrapped around the tumor edge. Segmentation: 68GY times, 3 times a week. Results The clinical symptom improvement was 100%. The effective rate of imaging was 85.7%. There was no difference between the 6GY and 8GY groups when the total biological dose was the same. 18 cases of portal vein tumor thrombus disappeared completely, 7 cases subsided most, 3 cases of carcinoma A slight reduction of the bolt, all patients to improve clinical symptoms, prolong survival. Conclusion Three-dimensional stereotactic stereotactic radiotherapy for hepatocellular carcinoma with portal vein tumor thrombus in patients with immediate effect, the clinical application worth promoting