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急性播散性金葡菌病常见于学龄儿童,半数以上有外伤史,该病的常见症状为高热,皮肤常见各种不同的皮疹和脓疱疹。19例中侵犯的器官例次为肺13、关节13、心包11、骨9、软组织4、脑膜3、心内膜2;并出现相应器官的症状和体征。各组织化脓性损害发展迅速,虽经敏感抗生素治疗,但病情好转缓慢,平均住院日45.8±20.8天。骨关节炎多转变为慢性。心内膜炎、心包炎、肺炎和脑膜炎病死率较高,死亡6例均伴有以上一处或数处炎症病灶,病死率为31.6％。细菌对青霉素和新青Ⅱ多不敏感,对其它常用抗生素的敏感性也较差,有待开发新的治疗方法和治疗药物。
Acute disseminated Staphylococcus aureus common in school-age children, more than half have a history of trauma, the common symptoms of the disease is fever, the skin is common in a variety of different rash and impetigo. 19 cases of infiltrated organs cases lung 13, joint 13, pericardium 11, bone 9, soft tissue 4, 3 meningeal, endocardial 2; and the corresponding organ symptoms and signs. Various organizations purulent damage developed rapidly, although the treatment by sensitive antibiotics, but the condition improved slowly, the average length of stay 45.8 ± 20.8 days. Osteoarthritis and more into chronic. Endocarditis, pericarditis, pneumonia and meningitis higher mortality, 6 cases were associated with death above one or more of the inflammatory lesions, the case fatality rate was 31.6%. Bacteria are more insensitive to penicillin and xinqing Ⅱ, the sensitivity of other commonly used antibiotics is also poor, pending the development of new treatments and therapies.