散发性脑膜炎球菌病患者的先天性或获得性补体缺陷

• 作 者: 王耀宗
• 出 处: 国外医学(免疫学分册)
• 发表日期: 1984年03期
• 关键词: 脑膜炎球菌病 补体缺陷 补体系统 荚膜多糖疫苗 免疫扩散法 急性症状 高滴度 多发性骨髓瘤 水痘脑炎 重症乙型肝炎

作者测定了20例散发性脑膜炎球菌感染者的补体系统,以进一步了解补体缺陷与脑膜炎球菌病之间的关系。20例患者均为首次催患脑膜炎球菌病,其中12例表现为脑膜炎,2例为急性败血症,4例兼有脑膜炎和败血症,另2例分别为慢性败血症和心包炎。20例中,12例属前瞻性研究,即发病前或急性症状缓解时测定补体者;8例于患病后测定补体,属回顾性研究。

The authors measured the complement system in 20 patients with sporadic meningococcal infection to further understand the relationship between complement defects and meningococcal disease. Twenty patients were the first to have meningococcal disease, of which 12 were meningitis, 2 were acute sepsis, 4 were meningitis and septicemia, and the other 2 were chronic sepsis and pericarditis. Of the 20 patients, 12 were prospective studies that measured complement before or during acute symptom relief; and 8 had complement disease after the illness, a retrospective study.