Synthesis, Crystal Structure and Biological Evaluation of Acridine-1,2,3-triazole Derivatives

• 作 者: HUOLi-Ni CHENRui LIAOYan-Fang
• 机 构: CollegeofPharmacy,FacultyofChineseMedicineScience,GuangxiResearchInstituteofChemicalIndustry,Guangxi
• 出 处: 结构化学
• 发表日期: 2016年5期
• 关键词: 生物学评价 晶体结构 衍生物 合成 X-射线衍射 X射线分析 Π-Π作用 抗肿瘤活性 acridine-1 2 3-triazole crystal struc
• 基金项目: Supported by the National Natural Science Foundation of China（No.51263002）, Natural Science Foundation of Guangxi Province（No.2014GXNSFBA118182）, the Scientific Research Fund of Guangxi Provincial Edu

A series of acridine-1,2,3-triazole derivatives were designed, synthesized and characterized by NMR. 1-(2-methylacridinyl)-4-(4-methyl phenyl)-1,2,3-triazole(4f), C_(23)H_(18)N_4, was structurally determined by single-crystal X-ray diffraction. It crystal