Lipopolysaccharide Challenge Induces Long Pentraxin 3 Expression in Mice Independently from Acute

• 作 者: Gao Zeng Jie Liu Ning Wu Cong-
• 机 构: DepartmentofEmergencyMedicine,DepartmentofThoracicSurgery,DepartmentofEmergencyMedicine
• 出 处: 中国医学科学杂志：英文版
• 发表日期: 2015年1期
• 关键词: 急性肺损伤 脂多糖 小鼠 诱导 穿透 支气管肺泡灌洗液 液体浓度 MRNA水平 long pentraxin 3 acute lung injury bio
• 基金项目: Partly supported by a grant from Jie-shou Li Academician Gut Barrier Research Fund.

Objective To determine whether the onset of acute lung injury(ALI) induces the up-regulation of pentraxin 3(PTX3) expression in mice and whether PTX3 concentration in the biofluid can help recognizing sepsis-induced ALI. Methods Wild-type C57BL/6 mice(12-