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报道我院1990~1991年对四川省泸县玄滩区157例大伤患者用国产地鼠肾细胞狂犬病疫苗进行免疫程序研究。在157例犬伤患者按不同免疫程序随机抽样分为4组,在免疫前(即O日)和免疫后15,30,60,90,180日取血分离血清,6次血清进行一次检测。其结果以Ⅲ组和Ⅳ组产生的保护性抗体效价较满意,在30日出现较高,维持时间最长(180日),均有高度显著性差异(P<0.005)。Ⅲ组免疫程序可节约一剂疫苗,减少两次注射时间,又达到保护作用,为此,我们推荐Ⅲ给免疫程序.
Report from our hospital from 1990 to 1991, 157 cases of Xuan Tan District, Sichuan Province, Xuan Tan area of patients with domestic hamster kidney cell rabies vaccine immunization program. 157 cases of canine injury patients were randomly divided into 4 groups according to different immunization procedures. Serum was separated from serum before immunization (ie day 0) and after immunization on days 15, 30, 60, 90 and 180, and 6 sera were tested. As a result, the titer of protective antibody produced by group Ⅲ and group Ⅳ was relatively satisfactory, which showed a high titer on the 30th and the longest (180th) for the maintenance time (P <0.005). Group Ⅲ immunization program can save a dose of vaccine, reducing the injection time twice, but also to achieve the protective effect, therefore, we recommend Ⅲ to the immune program.