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目的 :考察妇炎康复片 (败酱草 ,薏苡仁 ,川楝子 ,柴胡 ,黄芩 ,赤芍等 )的抗炎、止痛、抗菌、活血化瘀作用。方法 :以小鼠耳肿胀和大鼠足跖肿胀法 ,考察其抗炎作用 ;以小鼠扭体法 ,考察其止痛作用和体内保护试验法检测其抗菌活性 ;以肾上腺素引起微循环障碍造成大鼠血瘀模型 ,研究其活血化瘀作用。结果 :实验证明妇炎康复片有明显的抑制小鼠耳肿胀和大鼠足跖肿胀作用 (P <0 .0 1) ;具有明显的抑制小鼠产生扭体的作用 ,(P <0 .0 1) ;体内抗菌试验证实其可提高大肠杆菌感染小鼠的生存率还可降低血瘀大鼠全血高、中、低切粘度 ,血浆粘度、全血还原粘度和红细胞压积。结论 :妇炎康复片的药效与治疗临床慢性盆腔炎相一致
Objective : To investigate the anti-inflammatory, analgesic, antibacterial, and blood circulation effects of Fuyan Rehabilitation Tablets (pastoridium, Coix Seed, Chuanxiong Zi, Bupleurum, Radix Astragali, Radix Paeoniae Rubra etc.). METHODS: The mouse ear swelling and rat paw edema were used to examine the anti-inflammatory effects. The anti-inflammatory effects of the mice were tested by the twisting method, the analgesic effect and the in vivo protection test, and the microcirculatory disturbance induced by epinephrine. Rat blood stasis model was used to study the effect of promoting blood circulation and removing blood stasis. RESULTS: It was proved by the experiment that FuYiKang KangPian has obvious effect on inhibiting ear swelling and paw engorgement in rats (P < 0.01); it has a significant effect in inhibiting mouse writhing, (P <0. 1) In vivo antibacterial test confirmed that it can increase the survival rate of mice infected with E. coli can also reduce the whole blood high, medium and low cut viscosity, plasma viscosity, whole blood reduced viscosity and hematocrit. Conclusion: The efficacy of Fuyan Kangfu Tablet is consistent with the clinical treatment of chronic pelvic inflammatory disease