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探讨鼻腔原发性non-Hodgkin’s淋巴瘤(NHL)的诊断及其分类分期与预后的关系。方法:对10例鼻腔原发性NHL资料进行回顾性分析。结果:鼻腔原发性NHL均经病理检查证实,其分类分期与治疗效果密切相关;随访7例,其中5例T细胞恶性淋巴瘤(T-ML)伴全身症状者均于4~6个月内死亡,1例早期T-ML者治疗后健在无复发,1例B细胞恶性淋巴瘤者治疗后生存2.5年。结论:对鼻腔可疑病灶须反复活检,以求早期诊断;鼻腔原发性T-ML晚期者预后极差。
To investigate the diagnosis of primary non-Hodgkin’s lymphoma (NHL) in nasal cavity and the relationship between classification stage and prognosis. Methods: A retrospective analysis of 10 cases of primary NHL in the nasal cavity was performed. RESULTS: The primary nasal NHL was confirmed by pathological examination. The classification stage was closely related to the therapeutic effect. Seven cases were followed up, and 5 cases of T-cell lymphoma (T-ML) with systemic symptoms were all in 4 to 6 months. Internal death, 1 case of early T-ML patients survived without recurrence, and 1 case of B-cell lymphoma survived 2.5 years after treatment. Conclusion: The suspicious lesions in the nasal cavity must be biopsied for early diagnosis. The prognosis of the late primary T-ML in the nasal cavity is very poor.