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目的：探讨小儿支原体肺炎炎性细胞因子变化及其意义。方法：应用ＥＬＩＳＡ 双抗体夹心法检测了４５ 例经病原学及临床明确诊断的小儿支原体肺炎血清白细胞介素６、白细胞介素８。结果：二者水平在支原体肺炎急性期明显高于对照组（Ｐ＜ ０．０１），恢复期接近对照组（Ｐ＞ ０．０５）。结论：这两种炎性细胞因子在支原体肺炎发病机理中起重要作用，其水平与病情严重程度及产生的早期抗体效价水平相平行，对研究其发病机理及提供免疫治疗有指导意义
Objective: To investigate the changes of inflammatory cytokines in children with mycoplasmal pneumonia and its significance. Methods: Serum interleukin - 6 and interleukin - 8 in 45 children with mycoplasma pneumonia were detected by etiological and clinical diagnosis with ELISA double antibody sandwich method. Results: The levels of both were significantly higher in the acute phase of mycoplasma pneumonia than those in the control group (P <0.01), and the recovery time was close to the control group (P> 0.05). Conclusion: These two inflammatory cytokines play an important role in the pathogenesis of mycoplasma pneumonia. The level of these two inflammatory cytokines parallels the severity of the disease and the level of the early antibody titer. It is instructive to study its pathogenesis and provide immunotherapy