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A series of novel anthranilic diamides with benzyl sulfide scaffold were synthesized,in which N-pyridylpyrazole moiety generally regarded as key pharmacophore was abandoned.The target compounds were characterized by ~1H NMR,~(13)C NMR,~(19)F NMR and HRMS.The preliminary bioassays indicated that half of the title compounds were endowed with good insecticidal activities against armyworm(Mythimna sepatara) at the concentration of 500 mg/L,Exhilaratingly,the synthesized compound 3a was also active against Tetranychus cinnabarinus at 100 mg/L.The difference in activities between the target compounds was influenced by the substituents,which provided some hints for further investigation on structure modifications.
A series of novel anthranilic diamides with benzyl sulfide scaffold were synthesized, in which N-pyridylpyrazole. Compounds generally characterized as key pharmacophore was abandoned. The compounds of the invention were characterized by ~ 1H NMR, ~ (13) C NMR, ~ (19) F NMR and HRMS. The preliminary bioassays indicated that half of the title compounds were endowed with good insecticidal activities against armyworm (Mythimna sepatara) at the concentration of 500 mg / L, Exhilaratingly, the synthesized compound 3a was also active against Tetranychus cinnabarinus at 100 mg / L.The difference in activities between the target compounds was influenced by the substituents, which provided some hints for further investigation on structure modifications.