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作者选45岁以上发病的全身性红斑性狼疮(SLE)8例,50岁以上发病的类风湿关节炎(RA)40例,进行性全身性硬化症12例,多发性肌炎11例,各组均与青年发病组作对照。结果发现,高龄发病的SLE胸膜炎、造血脏器障碍呈有意义之高率,而皮疹、雷诺现象、肾病综合征、DNA抗体高值、DNA抗体阳性之百分率则低。需大剂量类固醇制剂治疗者较少,复发率低;高龄发病的RA经X光检查,关节破坏进行较迟。皮下结节、下肢浮肿、肺纤维化出现率高,而淋巴结肿大和γ-球蛋白血症出现率低;高龄发病的进行性全身性硬化症及多发性肌炎病人,除间质性肺病变发病率高外,未见其他特征。
Eighty patients with systemic lupus erythematosus (SLE), 40 with rheumatoid arthritis (RA), 50 with progressive systemic sclerosis, 12 with progressive systemic sclerosis and 11 with polymyositis Groups were compared with the young onset group. The results showed that senile SLE pleurisy, hematopoietic disorders showed a high rate of significance, and rash, Raynaud’s phenomenon, nephrotic syndrome, DNA antibody high value, DNA antibody positive percentage is low. The need for large doses of steroid treatment less, the recurrence rate is low; senile RA by X-ray examination, joint destruction later. Subcutaneous nodules, lower extremity edema, high incidence of pulmonary fibrosis, and lymph nodes and γ-globulin hyperlipidemia; advanced onset of progressive systemic sclerosis and polymyositis patients, in addition to interstitial lung disease High incidence, no other features.