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以异体垂体前叶植入的方法制造大鼠慢性高催乳素血症模型，研究人参茎叶皂甙（ＧｉｎｓｅｎｇＳｔｅｍａｎｄＬｅａｖｅＳａｐｏｎｉｎ，ＧＳＬＳ）对高催乳素血症大鼠催乳素（Ｐｒｏｌａｃｔｉｎ，ＰＲＬ）的作用。结果是：垂体前叶移植大鼠血清ＰＲＬ升高而原位垂体ＰＲＬ含量降低，ＧＳＬＳ则使高催乳素血症大鼠血清ＰＲＬ水平降低，原位垂体的ＰＲＬ含量降低。上述结果提示ＧＳＬＳ对高催乳素血症大鼠催乳素分泌有抑制作用。
A rat model of chronic hyperprolactinemia was established by implantation of anterior pituitary allograft. The effect of Ginseng Stemand Leave Saponin (GSLS) on prolactin (PRL) in hyperprolactinemia rats was studied. The result was that the serum PRL in the anterior pituitary transplanted rats increased and the pituitary PRL content decreased, while the GSLS reduced the serum PRL level in the hyperprolactinemia rats and decreased the PRL content in the orthotopic pituitary gland. The above results suggest that GSLS can inhibit prolactin secretion in hyperprolactinemia rats.