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目的了解文成县肺结核病人治愈情况以及治疗失败原因,以进一步提高肺结核病人的DOTS管理质量和治愈率。方法对全县2010年7月1日-2011年6月30日登记治疗的所有肺结核病人进行追踪调查,按历史前瞻性研究方法,对相关数据进行分析。结果调查期间共发现肺结核病人182例,治愈率为73.6%。影响治愈率的主要因素是治疗状况,经统计学分析各组间有统计学意义差异(χ2=159.884,P<0.05);婚姻状况、有无工作、吸烟、体重指数、患病史、不良反应、空洞和痰菌结果等因素对治愈率均没有明显影响;年龄、有无症状、文化程度、经济的独立性和是否独居等因素通过影响病人的治疗行为,导致不同的治疗结局。结论要提高肺结核治愈率最关键的是加强对病人的治疗管理,制定切合基层实际的治疗管理模式,完善长效机制,督促病人坚持按医师确定的治疗方案完成治疗,减少中断和间断治疗情况的发生。
Objective To understand the cure of tuberculosis patients in Wencheng County and the causes of treatment failure so as to further improve the management quality and cure rate of DOTS in tuberculosis patients. Methods All patients with tuberculosis registered for treatment from July 1, 2010 to June 30, 2011 in the county were followed up and analyzed according to historical prospective research methods. Results A total of 182 pulmonary tuberculosis cases were found during the investigation, with a cure rate of 73.6%. The main factors influencing the cure rate were the treatment status. There was a statistically significant difference among the groups (χ2 = 159.884, P <0.05) by statistical analysis; marital status, work or not, smoking, body mass index, medical history, adverse reactions , Voids and sputum bacterium results and other factors have no significant effect on the cure rate; age, asymptomatic, educational level, economic independence and whether alone living and other factors affect the patient’s treatment behavior, leading to different treatment outcomes. Conclusion To improve the cure rate of tuberculosis, the most important is to strengthen the treatment and management of the patients, to formulate the actual treatment and management model at the grassroots level, to perfect the long-term mechanism, to urge the patients to adhere to the treatment scheme determined by the physician to complete the treatment, reduce disruption and intermittent treatment occur.