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目的探讨血清C反应蛋白(CRP)与脑梗死的关系。方法用免疫透射比浊法测定120例脑梗死患者血清CRP含量,并与105名健康体检者进行对照,同时对脑梗死患者血清CRP水平与病情进行相关分析。结果脑梗死组血清CRP水平高于正常对照组(P<0.01);脑梗死不同临床分型间血清CRP水平比较:大梗死组高于中梗死组、小梗死组,重型组高于中型、轻型组,差异均有显著性(均P<0.01)。结论CRP水平是临床评价脑梗死严重程度和预后的一个重要的生物学指标。急性脑梗死患者血清CRP水平升高提示病情重、预后差。适时减轻炎症反应损害,可以降低脑梗死的发病率及改善预后。
Objective To investigate the relationship between serum C-reactive protein (CRP) and cerebral infarction. Methods Serum CRP levels were measured in 120 patients with cerebral infarction by immunoturbidimetry and compared with 105 healthy subjects. Correlation analysis was made between serum CRP levels and the severity of the disease. Results Compared with normal control group, serum CRP level in cerebral infarction group was significantly higher than that in normal control group (P <0.01). CRP levels in different infarction groups were higher than those in middle infarction group, small infarction group and severe group Group, the differences were significant (all P <0.01). Conclusion The CRP level is an important biological index for clinical evaluation of the severity and prognosis of cerebral infarction. Patients with acute cerebral infarction elevated serum CRP levels suggest that the disease, the prognosis is poor. Timely reduce inflammation damage, can reduce the incidence of cerebral infarction and improve prognosis.