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本文报告12例肝硬化顽固性腹水行血液透析浓缩回输治疗,其方法是在无菌条件下,按一定的流速腹水完全放完为止。本组病例每次放腹水2700~6000ml,平均3500ml,经血液透析器超滤、脱水,浓缩8~10倍后再静脉回输。放腹水及浓缩回输前后,均监测呼吸、脉博、血压,及测定浓缩前后腹水蛋白浓度,回输后血浆蛋白浓度及24小时尿量。经治疗后,所有病例在1~6周内经1~4次腹水浓缩回输,腹水完全清除。无不良反应,回输后病人血浆白蛋白浓度升高0.5~1.0g/d1,肾功能改善,尿量明显增加,饮食及精神状态改善明显。对再发病例,再次浓缩回输仍有效。从而提示经血液透析腹水浓缩回输术,对肝硬化顽固性腹水,具有良好的疗效,且安全可靠。
This article reports 12 cases of cirrhosis refractory ascites hemodialysis concentrated back to the treatment, the method is under sterile conditions, according to a certain flow rate as soon as the complete release of ascites. The patients in each group ascites 2700 ~ 6000ml, an average of 3500ml, by the hemodialyzer ultrafiltration, dehydration, concentrated 8 ~ 10 times after intravenous infusion. Ascites and the concentration before and after reinfusion, were monitoring respiration, pulse, blood pressure, and determination of concentration of ascites protein concentration before and after the return of plasma protein concentration and 24-hour urine output. After treatment, all cases in 1 to 6 weeks 1 to 4 times the concentration of ascites transfusion, ascites completely removed. No adverse reactions, the patient’s plasma albumin concentration after the return increased 0.5 ~ 1.0g / d1, renal function improved, urine output increased significantly, diet and mental status improved significantly. For recurrent cases, again concentrated return is still valid. Thus prompted by hemodialysis ascites concentrated transfusion surgery, cirrhosis and refractory ascites, has a good effect, and safe and reliable.