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目的:研究辛伐他汀治疗高血脂症的临床疗效并对其用药安全性进行分析。方法:选取高血脂患者88例,每晚服用辛伐他汀分散片20mg,并持续用药2个月。对比患者治疗前后的血常规、肝肾功能等指标。结果:治疗前患者TC、TG、HDL-C、LDL-C分别为(6.65±0.71)mmol/L、(2.44±0.61)mmol/L、(1.12±0.6 8)mrmol/L和(5.21±0.63)mmol/L,治疗后分别为(4.11±0.35)mmol/L、(1.78±0.46)mmol/L、(1.42±0.51)mmol/L和(2.43+0.57)mmol/L,差异均具体统计学意义(P<0.05);治疗期间未对患者肝肾等功能造成影响。结论:辛伐他汀治疗高血脂症的临床效果显著,不良反应程度较低,具有良好的临床安全性,值得推广应用。
Objective: To study the clinical efficacy of simvastatin in the treatment of hyperlipidemia and analyze the safety of its use. Methods: 88 patients with hyperlipidemia were selected, and 20 mg of simvastatin dispersible tablets were taken every night for 2 months. Before and after treatment compared to patients with blood, liver and kidney function and other indicators. Results: The levels of TC, TG, HDL-C and LDL-C in patients before treatment were (6.65 ± 0.71) mmol / L, (2.44 ± 0.61) mmol / L, (1.12 ± 0.6 8) (4.11 ± 0.35) mmol / L, (1.78 ± 0.46) mmol / L, (1.42 ± 0.51) mmol / L and (2.43 + 0.57) mmol / L respectively after treatment. The differences were statistically significant Significance (P <0.05); during treatment did not affect the function of patients such as liver and kidney. Conclusion: The clinical effect of simvastatin in treatment of hyperlipidemia is significant, the degree of adverse reactions is low, it has good clinical safety and is worth popularizing and applying.