Deletion of IFT20 in early stage T lymphocyte differentiation inhibits the development of collagen-i

• 作 者: Xue Yuan Lee Ann Garrett-Sinha
• 机 构: DepartmentofOralBiology,DepartmentofBiochemistry,LaboratoryforBiomaterialsandRegenerativeTherapeutic
• 出 处: 骨研究：英文
• 发表日期: 2014年4期
• 关键词: 早期阶段 关节炎 T淋巴细胞 CRE重组酶 诱导 胶原 T细胞发育 转基因小鼠
• 基金项目: supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases,part of the National Institutes of Health,under Award Numbers AR055678,DE023105 and AR061052 to SY

IFT20 is the smallest member of the intraflagellar transport protein(IFT) complex B. It is involved in cilia formation. Studies of IFT20 have been confined to ciliated cells. Recently, IFT20 was found to be also expressed in non-ciliated T cells and have