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为观察天普洛欣尿激酶(TP UK)溶栓治疗早期急性脑梗塞的疗效和副作用,以及动静脉不同应用途径的疗效差别。采用动脉组50万~u,5分钟内注入,静脉组100~150万~u,半小时内滴入,设对照组并不使用溶栓药物。治疗前及治疗后多次做神经功能缺损评分以判定疗效,同时观察副作用的发生率。结果TPUK动静脉溶栓组治疗后各溶栓段神经功能缺损评分较溶栓前比较,有显著的临床意义,各治疗组的总有效率明显高于对照蛆,动脉用药组在2小时的神经缺损改善情况优于静脉组,其余时间静脉组优于动脉组。TPUK所致出血的副作用发生率较对照组高。提示TPUK对早期急性脑梗塞有很好的治疗作用。
To observe the efficacy and side effects of thrombolysis with dipuvastin and urokinase (TP UK) in the treatment of early acute cerebral infarction, and to evaluate the efficacy of different routes of application for arteriovenous. Artery group 500000 ~ u, 5 minutes infusion, intravenous group 100 ~ 1.5 million ~ u, within half an hour of infusion, the control group did not use thrombolytic drugs. Before and after treatment, neurological deficit scores were made many times to determine the efficacy, and to observe the incidence of side effects. Results TPUK thrombolysis group after thrombolytic treatment of neurological deficit score compared with before thrombolysis, has a significant clinical significance, the total effective rate of each treatment group was significantly higher than the control maggots, arterial medication group 2 hours in the nerve Defects improved better than the vein group, the rest of the vein group is better than the artery group. TPUK caused by the side effects of bleeding than the control group. Tip TPUK early acute cerebral infarction has a good therapeutic effect.