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我们于1991年3月～12月用环丙氟哌酸(500mg、q12h)治疗30例伤寒,结果伤寒高峰热下降时间不超过24小时,退热时间48小时到5天,平均3天。临床有效率为100%。现报道如下。对象与方法一、病例选择男性16例,女性14例。年龄24～55岁,平均年龄32岁。热型大部份为稽留热,少数几例为弛张热或不规则热,平均体温39.2℃。30例中血培养阳性19例,肥达氏反应阳性30例,30例中并发肠出血1例,并发胆囊炎者3例,重症患者4例。二、治疗方法环丙氟哌酸500mg,q12h。重症患者750mg,q12h。该药由美国国际化工贸易香港有限公司提供。疗程8～15天,平均疗程10天。三、疗效判断标准(1)痊愈:临床症状体征消失,各项化验恢复正常,血培养阴性或大便培养连
We treated 30 cases of typhoid fever with ciprofloxacin (500mg, q12h) from March to December 1991, resulting in a decrease in typhoid fever peak time of no more than 24 hours and an antipyretic time of 48 hours to 5 days with an average of 3 days. The clinical effective rate is 100%. Report as follows now. Objects and methods A case selection of 16 males and 14 females. Aged 24 to 55 years old, average age 32 years old. Most of the hot type for the retention of heat, a few cases of relaxation or irregular heat, the average body temperature of 39.2 ℃. In 30 cases, 19 were positive for blood culture, 30 were positive for Widal reaction, 1 was complicated by intestinal hemorrhage in 30 patients, 3 were complicated by cholecystitis and 4 were severe patients. Second, the treatment of Ciprofloxacin 500mg, q12h. Severe patients 750mg, q12h. The drug provided by the United States International Chemical Trading Hong Kong Limited. Course of 8 to 15 days, the average course of 10 days. Third, the efficacy of judgment criteria (1) cured: clinical symptoms and signs disappeared, the test returned to normal, blood culture or stool with negative