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概念:以肺出血和急进性肾炎为主要特征的综合征,1919年 Goodpasture 首先报导一例18岁男性患者,虽然流感症状缓解但其后一个月发生咳血贫血继而合并有重症肾炎六周后死亡,剖检发现肺泡内显著出血和噬铁细胞(Siderop-hage),在组织学上肾脏呈现增殖型肾小球肾炎的徵象,其后1958年 Stanton 报告21例并提倡此病从临床及病理学上所见为一独立疾患而命名为 Goodpasture 综合征。
Concept: Pulmonary hemorrhage and progressive nephritis as the main features of the syndrome, 1919 Goodpasture first reported an 18-year-old male patient, although the flu symptoms were alleviated but the month after cough and anemia followed by severe nephritis with death after six weeks, An autopsy revealed significant alveolar hemorrhage and siderop-hage, which histologically presented with signs of proliferative glomerulonephritis. Stanton subsequently reported 21 in 1958 and advocated the clinical and pathological Visited as an independent disorder named Goodpasture syndrome.