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目的讨论血液净化在抢救急性重度有机磷农药中毒的临床疗效。方法对58例收住ICU的急性重度有机磷农药中毒的患者随机分组。治疗组(n=28),对照组(n=30)。治疗组:急性重度AOPP28例,在内科综合治疗的基础上加用血液净化治疗。对照组:同期收住的未能行血液净化治疗,尽使用内科综合治疗的AOPP患者。比较观察在呼吸机的脱机时间,意识恢复时间,胆碱酯酶恢复时间,并发症的发生率,治愈率,死亡率。结果与对照组相比,治疗组意识恢复时间和CHE恢复时间快,脱机时间早,治愈率高,并发症发生率低。结论内科综合治疗是抢救重度AOPP的关键,血液净化可以缩短AOPP的病程,减少并发症的发生率,提高治愈率。
Objective To discuss the clinical efficacy of blood purification in salvage acute severe organophosphorus pesticide poisoning. Methods Fifty-eight patients with acute severe organophosphorus pesticide poisoning in ICU were randomly divided into groups. Treatment group (n = 28), control group (n = 30). Treatment group: Acute severe acute ophthalmic AOPP 28 cases, combined with medical treatment based on blood purification treatment. Control group: the same period failed to receive admission blood purification treatment, make the best use of comprehensive medical treatment of AOPP patients. Compare the time of respirator offline, conscious recovery time, cholinesterase recovery time, the incidence of complications, cure rate, mortality. Results Compared with the control group, the recovery time and CHE recovery time of the treatment group were quick, the off-line time was earlier, the cure rate was high, and the complication rate was low. Conclusion The comprehensive medical treatment is the key to rescue severe AOPP. Blood purification can shorten the course of AOPP, reduce the incidence of complications and improve the cure rate.