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目的评价永城市对不同对象实施不同休止期治疗(简称休治)的效果,为制定疟疾防治对策提供依据。方法选择永城市马桥、李寨和裴桥乡为试点,以行政村为单位根据2006年发病率采取不同的休治方法,发病率≥1%的3个行政村实施全民休治,确定全体常住人口为休治对象;发病率<1%的1个行政村实施病家四邻服药,确定疟史患者、患者家属及其四周邻居为休治对象。确定的休治对象在春季疟疾休止期均给予氯喹/伯喹8d8次服药治疗。收集当年疟疾发病个案调查表、疫情报表和统计表,分析比较疟疾发病情况。结果全民休治村2007年疟疾发病率为0.7%(42/5618),较上年2.3%的发病率下降69.6%,差异有统计学意义(χ2=44.947,P<0.001);实施病家四邻服药村发病率0.4%(8/1955),较上年0.9%的发病率下降55.6%,但差异无统计学意义(χ2=3.261,P=0.071)。10月份以前全民休治行政村月累计疟疾发病率与病家四邻服药村比较差异无统计学意义(χ2=0.501,P=0.479),两组群全年发病率差异也无统计学意义(χ2=2.532,P=0.112)。结论对疟疾发病率≥1%的行政村实施全民休治可扭转疫情上升势头,对发病率<1%的行政村实施病家四邻服药可遏制疫情上升势头。
Objective To evaluate the effect of different kinds of rest period treatment (referred to as rest period) on different subjects in Yongcheng City and provide the basis for malaria prevention and control measures. Methods Maqiao, Lizhai and Peiqiao Township in Yongcheng were chosen as pilot projects. Three administrative villages with morbidity of 1% or more were treated according to the incidence of 2006 according to the incidence of 2006 as the pilot. Resident population is the object of treatment; morbidity <1% of an administrative village to implement the disease around the medication, to determine the history of malaria patients, their families and their neighbors for the rest of the object. Confirmed subjects for treatment were given chloroquine / primaquine 8d8 times in the spring malaria suspension period. Collect malaria case questionnaire, epidemic situation report and statistical table of the year, analyze and compare the incidence of malaria. Results In 2007, the incidence of malaria was 0.7% (42/5618) in Huazhu Village, down by 69.6% from the incidence of 2.3% in the previous year (χ2 = 44.947, P <0.001) The incidence of medication in the village was 0.4% (8/1955), down 55.6% from the 0.9% in the previous year, but the difference was not statistically significant (χ2 = 3.261, P = 0.071). Before October, the cumulative incidence of malaria in the administrative sub-district of Huzhu County had no significant difference with the incidence of malaria in neighboring villages (χ2 = 0.501, P = 0.479), and there was no significant difference in annual incidence between the two groups (χ2 = = 2.532, P = 0.112). Conclusion The implementation of universal suffrage in the administrative villages with the incidence of malaria ≥1% can reverse the upward trend of epidemic situation, and the implementation of the administration of four neighbors in administrative villages with incidence of less than 1% can curb the upward trend of epidemic situation.