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恶性肿瘤血清可溶性白细胞介素2受体（SIL－2R）水平增高是由肿瘤诱导的免疫反应所致。大肠癌血清SIL－2R水平明显比正常人群高，且与大肠癌临床分期有关，根治性大肠癌切除术后2周SIL－2R可降至正常水平。研究表明sIL－2R水平与大肠癌患者的免疫状态及病情严重程度有关。
Increased levels of serum soluble interleukin 2 receptor (SIL-2R) in malignant tumors are caused by tumor-induced immune responses. The serum level of SIL-2R in colorectal cancer was significantly higher than that in the normal population and was related to the clinical stage of colorectal cancer. SIL-2R was reduced to normal levels at 2 weeks after radical resection of colorectal cancer. Studies have shown that the level of sIL-2R is related to the immune status and the severity of illness in patients with colorectal cancer.