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目的探讨载脂蛋白A-Ⅰ在预示妊娠期间发生自然流产的价值。方法采用免疫透射比浊法检测564例正常妊娠孕妇与126例自然流产孕妇以及200例健康非妊娠妇女的APOA-Ⅰ水平。结果发生异常妊娠自然流产的孕妇其载脂蛋白A-Ⅰ水平显著不同于同期正常妊娠妇女。妊娠期载脂蛋白A-Ⅰ与非妊娠期相比明显升高,而在妊娠过程中发生自然流产者,其APOA-Ⅰ大多与非妊娠者相一致。结论临床检测APOA-Ⅰ的水平,对了解妊娠过程的变化和指导治疗有一定的意义。
Objective To investigate the value of apolipoprotein A-Ⅰ in predicting spontaneous abortion during pregnancy. Methods The level of APOA-Ⅰ in 564 normal pregnant women, 126 spontaneous abortion pregnant women and 200 healthy non-pregnant women was detected by immunoturbidimetry. Results The level of apolipoprotein A-Ⅰ in pregnant women with spontaneous abortion of abnormal pregnancy was significantly different from that of normal pregnant women in the same period. Pregnancy apolipoprotein A-Ⅰ compared with non-pregnancy significantly increased, while spontaneous abortion during pregnancy, the APOA-Ⅰ mostly consistent with non-pregnant. Conclusion The level of APOA-Ⅰ in clinical examination has certain significance in understanding the changes of pregnancy process and guiding the treatment.