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目的对我院门诊抗菌药物使用情况进行分析,评价其合理性,规范抗菌药物的使用,促进合理用药。方法从我院2016年1月1日至6月30日的门诊处方中筛选出使用抗菌药物的处方,统计我院抗菌药物的使用情况,根据《抗菌药物临床应用指导原则》、《处方点评暂行管理规定(试行)》及药品说明书等,评价门诊抗菌药物处方的合理性。结果在121142张门诊处方中,含抗菌药物处方达6.56%,处方量7947张,使用频次8214次。其中儿科门诊开具的抗菌药物处方最多,比例达33.56%;注射剂型的抗菌药物比例为53.23%;头孢菌素类40.72%,大环内酯类18.64%;抗菌药物处方中不合理处方855张,处方合理率为89.24%,不合理用药主要表现在无指征用药、用法用量不合理等。结论我院门诊抗菌药物处方总体合理性较好,但仍存在一些问题,临床药师需加大对临床不合理用药的干预,加强抗菌药物的管理,保证临床用药安全。
Objective To analyze the use of antibacterials in outpatient clinics in our hospital, evaluate its rationality, standardize the use of antibacterials and promote the rational use of drugs. Methods From January 1, 2016 to June 30, our hospital outpatient prescriptions were screened out the use of antimicrobials prescriptions, statistics of the use of antimicrobial agents in our hospital, according to “guidelines for the clinical application of antimicrobial agents,” “Interview Comment Management Regulations (Trial) ”and drug instructions, etc., to evaluate the rationality of prescription antibacterial drugs. Results Among 121 412 outpatient prescriptions, prescriptions containing antimicrobials reached 6.56%, prescriptions were 7947 and frequency of use was 8214. Among them, antibacterial prescriptions issued by pediatric outpatients were the most, accounting for 33.56%; the proportion of antibacterials in injection form was 53.23%; 40.72% of cephalosporins and 18.64% of macrolides; 855 unreasonable prescriptions in antibacterial drugs, Prescription rate was 89.24%, irrational use of drugs mainly in the absence of indications for medication, dosage and other unreasonable. Conclusion The prescriptions of antibacterials in outpatient clinics in our hospital are generally reasonable, but there are still some problems. The clinical pharmacists need to increase their intervention in unreasonable use of medicines, and strengthen the management of antibacterials to ensure the safety of clinical medication.