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目的:观察谷胱甘肽对糖尿病神经病变的疗效。方法:28例糖尿病神经病变病人(男性12例,女性 16例,年龄 62 a± s 5 a)在应用降糖药较好控制血糖后加用谷胱甘肽 1.8 g加入 0.9%氯化钠注射液 250 mL静脉滴注,qd, 7~10 d为一个疗程,应用 2个疗程。结果:显效 18例,显效率 64%,有效 8例,总有效率 93%,肌电图示病人神经传导速度明显改善(P<0.05和P<0.01)。结论:谷胱甘肽是治疗糖尿病神经病变的良好药物。
Objective: To observe the effect of glutathione on diabetic neuropathy. Methods: Twenty-eight diabetic neuropathy patients (12 males and 16 females, aged 62 ± 5 years) were treated with hypoglycemic agents to control blood sugar and added with 1.8 g glutathione (0.9% Sodium chloride injection 250 mL intravenous infusion, qd, 7 ~ 10 d for a course of treatment, the application of 2 courses. Results: 18 cases were markedly effective, 64% effective, 8 effective and 93% effective. Electromyography showed that the nerve conduction velocity was significantly improved (P <0.05 and P <0.01). Conclusion: Glutathione is a good drug for the treatment of diabetic neuropathy.