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目的研究观察同步放疗联合奈达铂、紫杉醇在宫颈癌治疗中的临床效果。方法选择2012-02-2015-02我院收治的48例宫颈癌患,按治疗方法分为联合组和对照组。联合组采用同步放疗联合奈达铂+紫杉醇治疗,对照组采用单纯同步放疗进行治疗,对比两组患者治疗效果。结果联合组肿瘤缓解总有效率为87.5%,对照组58.33%,数据比较差异均具有统计学意义,P<0.05;联合组各项不良反应发生率高于对照组,数据比较差异不具有统计学意义,P>0.05;随访12个月,联合组总生存率83.3%、无远处转移生存率75.0%、无局部复发率79.2%均明显高于对照组54.2%、45.8%、50%,数据比较差异具有统计学意义,P<0.05。结论同步放疗联合奈达铂+紫杉醇治疗可对肿瘤达到有效缓解,改善肿瘤分期,提高患者生存率,具有较高安全性,治疗效果显著。
Objective To observe the clinical effect of synchrotron radiation combined with nedaplatin and paclitaxel in the treatment of cervical cancer. Method selection 2012-02-2015-02 48 cases of cervical cancer admitted to our hospital, according to the treatment method is divided into the combined group and the control group. The combination group treated with syndetradiation combined with nedaplatin + paclitaxel, the control group treated with synchrotron radiation alone, the treatment effect was compared between the two groups. Results The total effective rate of tumor remission was 87.5% in the combined group and 58.33% in the control group, the difference was statistically significant (P <0.05). The incidence of adverse reactions in the combination group was higher than that in the control group, and the difference was not statistically significant Significance, P> 0.05; At the 12-month follow-up, the overall survival rate was 83.3% in the combination group, without distant metastasis survival rate 75.0%, without local recurrence rate 79.2%, significantly higher than the control group 54.2%, 45.8%, 50% The difference was statistically significant, P <0.05. Conclusions Synchronous radiotherapy combined with nedaplatin + paclitaxel can effectively relieve the tumor, improve the tumor staging, improve the survival rate, have higher safety and have a significant therapeutic effect.