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罗格列酮具有增加胰岛素敏感性、降低胰岛素抵抗而调节血糖的作用,临床广泛用于糖尿病的治疗。近年发现罗格列酮还在全身多器官、多系统的急慢性炎症病变中发挥着重要的抗炎作用。探索罗格列酮抗炎作用的机制可能为炎性疾病的治疗带来新的希望。
Rosiglitazone has the effect of increasing insulin sensitivity and reducing insulin resistance and regulating blood sugar. It is widely used in the treatment of diabetes. In recent years, rosiglitazone has also been found to play an important anti-inflammatory role in the systemic multiple organ and multiple system acute and chronic inflammatory diseases. Mechanisms to explore the anti-inflammatory effects of rosiglitazone may offer new hope for the treatment of inflammatory diseases.