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目的 观察直接PTCA对急性心肌梗死 (AMI)患者QT离散度 (QTd)及QTc离散度 (QTcd)的影响。方法 对 30例AMI患者行直接PTCA ,使病变血管血流达到TIMI血流 3级 ,于PTCA术前、术后 2h、4 8h作同步 12导心电图并测量QTd及QTcd ,然后与 30例正常人对照。结果 AMI组与正常对照组间QTd及QTcd有极显著差异 (P <0 .0 1)。有室性心律失常的AMI患者其QTd和QTcd高于无室性心律失常患者 ,但差异无显著性(P >0 .0 5 ) ,PTCA术后其QTd和QTcd下降 (P <0 .0 1) ,室性心律失常好转。结论 成功的直接PTCA可降低AMI患者的QTd和QTcd ,减少室性心律失常的发生 ,改善预后
Objective To observe the effect of direct PTCA on QT dispersion and QTc dispersion in patients with acute myocardial infarction (AMI). Methods Thirty patients with AMI underwent direct PTCA to achieve grade III TIMI flow. Preoperative PTCA, postoperative 2h and 48h were used to synchronize 12-lead electrocardiogram (ECG) and QTd and QTcd, and then to 30 normal subjects Control. Results There was a significant difference in QTd and QTcd between AMI group and normal control group (P <0.01). QTd and QTcd in patients with ventricular arrhythmias were higher than those in patients without ventricular arrhythmias, but there was no significant difference (P> 0.05), QTd and QTcd decreased after PTCA (P <0.01) ), Ventricular arrhythmias improved. Conclusion The successful direct PTCA can reduce QTd and QTcd in patients with AMI, reduce the occurrence of ventricular arrhythmias and improve prognosis