镁和维生素E补充对中老年女性血糖和血脂代谢影响的研究

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[目的]观察补充镁(Mg)和维生素E(VE)对中老年女性血糖和血脂代谢的影响。[方法]选取160名55~70岁中老年女性作为研究对象,随机分为对照(C),维生素E(E)、镁(M)和镁+维生素E(EM)4组,分别给予安慰剂、Mg、VE和Mg+VE,共3个月。通过膳食调查了解营养素摄入情况。干预前后分别采集空腹静脉血检测血糖及血脂指标。[结果]调查人群能量、钙、锌、铜摄入量不足。M组FBG干预后降低0.73mmol/L(P﹤0.05)。E、M和EM组TC干预后分别降低2.77mmol/L,2.47mmol/L和1.87mmol/L(P﹤0.01),与对照组相比差异均有统计学意义(P﹤0.01)。E、M和EM组HDL较干预前分别升高0.24mmol/L(P﹤0.01),0.22mmol/L(P﹤0.01)和0.17mmol/L(P﹤0.05)。对照组TG较干预前增高2.28mmol/L(P﹤0.01),E、M和EM各组TG比干预前分别降低2.83mmol/L,1.31mmol/L和2.39mmol/L(P﹤0.01)。[结论]补镁能显著降低空腹血糖水平,镁和/或维生素E补充均能有效地降低中老年女性血浆TC、TG,并提高HDL水平,提示镁和维生素E适量补充对改善中老年女性血糖、血脂代谢具有积极作用。 [Objective] To observe the effects of magnesium and vitamin E supplementation on blood glucose and lipid metabolism in middle-aged and elderly women. [Methods] A total of 160 middle-aged and aged women aged 55-70 were selected and randomly divided into 4 groups: control (C), vitamin E (E), magnesium (M) and magnesium plus vitamin E (EM) , Mg, VE and Mg + VE, a total of 3 months. Through dietary surveys to understand nutrient intake. Blood samples were collected before and after the fasting blood glucose and blood lipid indicators were collected. [Results] The survey population energy, calcium, zinc, copper intake is insufficient. M group FBG intervention decreased 0.73mmol / L (P <0.05). Compared with the control group, the TC levels in E, M and EM groups decreased by 2.77mmol / L, 2.47mmol / L and 1.87mmol / L, respectively (P <0.01). The levels of HDL in E, M and EM groups were increased by 0.24 mmol / L (P <0.01), 0.22 mmol / L (P <0.01) and 0.17 mmol / L (P <0.05) respectively before intervention. TG in control group increased 2.28mmol / L before intervention (P <0.01), and TG in E, M and EM groups decreased by 2.83mmol / L, 1.31mmol / L and 2.39mmol / L respectively compared with those before intervention (P <0.01). [Conclusion] Magnesium supplementation can significantly lower fasting blood glucose levels. Magnesium and / or vitamin E supplementation can effectively reduce plasma TC, TG and HDL levels in middle-aged and elderly women, suggesting that adequate supplementation of magnesium and vitamin E can significantly improve blood glucose , Lipid metabolism has a positive effect.
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