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目的研究甲基强的松龙(甲强龙)对儿童重症哮喘的治疗效果。方法取2010年1月至2012年12月于我院住院治疗的80例重症哮喘患儿,随机分为甲强龙组和对照组,每组40例,甲强龙组常规治疗基础上给予甲强龙2 mg/kg/次,Q8 h静滴;对照组常规治疗。观察两组患儿临床症状、体征、血氧饱和度及血气分析好转时间。对观察结果使用SPSS 13.0软件进行统计分析,组间差异比较采用t检验,P<0.05表示差异有统计学意义。结果发现甲强龙组哮喘儿童临床症状、体征恢复时间明显短于对照组,PaO2好转速度也快于对照组,P<0.05。结论甲强龙治疗儿童重症哮喘效果确切,可以迅速缓解喘息症状,缩短病程,在临床上可以推广使用。
Objective To study the therapeutic effect of methylprednisolone (methylprednisolone) on severe asthma in children. Methods From January 2010 to December 2012 in our hospital for treatment of 80 cases of severe asthma in children, were randomly divided into methylprednisolone group and control group, 40 cases in each group, methylprednisolone group based on conventional treatment to give a Strong dragon 2 mg / kg / times, Q8 h intravenous infusion; control group conventional treatment. The clinical symptoms, signs, blood oxygen saturation and blood gas analysis were observed in two groups. The observation results were analyzed by SPSS 13.0 software, t-test was used to compare the difference between the groups, P <0.05 means the difference was statistically significant. The results showed that the recovery time of clinical symptoms and signs of asthma children in methylprednisolone group was significantly shorter than that of the control group, and the improvement speed of PaO 2 was also faster than that of the control group (P <0.05). Conclusion Metronidazole treatment of severe acute asthma in children, can quickly relieve wheezing symptoms, shorten the course of the disease, can be used clinically.