正常眼压性青光眼半侧视野损伤及相应的视盘旁萎缩间的关系

来源 :世界核心医学期刊文摘.眼科学分册 | 被引量 : 0次 | 上传用户:sosmax68
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Purpose:To evaluate the correlation between the superior or inferior half area of parapapillary atrophy(PPA) and the corresponding hemifield visual field damage(VFD) in normaltension glaucoma.Design:Cross-sectional study.Methods:patients:One hundred nine eyes of 109 consecutive patients with normal-tension glaucoma.observation procedures:Topography parameters of the optic nerve head and PPA(zone β) area were obtained with the Heidelberg Retina Tomograph(HRT) ,and VFD was evaluated with the 30 to 2 program of Humphrey Field Analyzer.The HRT parameters and PPA area were determined separately in superior and inferior half regions.main outcome measures:Partial correlation coefficients of the superior and inferior areas of PPA with refractive error,axial length,HRT parameters,and corresponding hemifield VFD.Results:In simple correlation analyses,significant correlation was found between the inferior PPA area and the superior hemi-field VFD(Spearman rank correlation coefficient;Rs=-0.32;P <.001) but not between the superior PPA area and the inferior hemifield VFD(Rs=0.05;P=.6) .Age,refractive error,axial length,and height variation contour were associated significantly with the total,superior,and inferior areas of PPA,respectively(P<.01) .Multiple regression analyses showed that the superior PPA area was associated significantly with only axial length(P <.001) ,and the inferior PPA area was associated significantly with the axial length and the superior hemifield VFD(P<.001) .Conclusions:In patients with normal-tension glaucoma,only the inferior half area of PPA correlated significantly with glaucomatous VFD.Axial length and myopia were associated with both the superior and inferior half areas of PPA. Purpose: To evaluate the correlation between the superior or inferior half area of ​​parapapillary atrophy (PPA) and the corresponding hemifield visual field damage (VFD) in normal tetan glaucoma. Design: Cross-section study. Methods: patients: One hundred nine eyes of 109 consecutive patients with normal-tension glaucoma. observation procedures: Topography parameters of the optic nerve head and PPA (zone β) area were obtained with the Heidelberg Retina Tomograph (HRT), and VFD was evaluated with the 30 to 2 program of Humphrey Field Analyzer The HRT parameters and PPA area were determined separately in superior and inferior half regions. Main outcome measures: partial correlation coefficients of the superior and inferior areas of PPA with refractive error, axial length, HRT parameters, and corresponding hemifield VFD. Results: In simple correlation analyzes, significant correlation found between the inferior PPA area and the superior hemi-field VFD (Spearman rank correlation coefficient; Rs = -0.32; P < .001) but not between the superior PPA area and the inferior hemifield VFD (Rs = 0.05; P = .6). Age, refractive error, axial length, and height variation contour were associated significantly with the total, superior, and inferior areas of PPA, respectively (P <.01). Multiple regression analyzes showed that the superior PPA area was associated significantly with only axial length (P <.001), and the inferior PPA area was associated significantly with the axial length and the superior hemifield VFD (P <.001) .Conclusions: In patients with normal-tension glaucoma, only the inferior half area of ​​PPA correlated significantly with glaucomatous VFD. Axial length and myopia were associated with both the superior and inferior half areas of PPA.
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