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患男,6岁。因发热、咳嗽3d,鼻塞、流涕7d入院,诊断为支气管肺炎。询问无药物过敏史,在右前臂屈侧皮内注射青霉素G皮试液0.1ml,30min观察结果,局部无红肿及硬结,皮试阴性。根据医嘱给静脉滴注10％葡萄糖液150ml,内加青霉素480万U,静滴10min时,患儿面颊部出现潮红,继之眼睑也红肿,颜面部出现皮疹,压之不褪色。患儿述腹部不适,而四肢及躯干均无皮疹出现、心率90次/min,律齐,腹软,肠鸣音正常,追问病史,既往曾有2次类似情况,未引起注意,考虑与青霉素过敏有关,立即停用青霉素,换用洁霉素静滴,约3h后,患儿上述症状消失。
Male, 6 years old. Because of fever, cough 3d, nasal congestion, runny nose 7d admission, diagnosis of bronchial pneumonia. Asked no history of drug allergy, flexion in the right forearm intradermal injection of penicillin G skin test solution 0.1ml, 30min observation results, no local swelling and induration, skin test negative. According to doctor’s advice to intravenous infusion of 10% glucose solution 150ml, penicillin 4.8 million U, intravenous infusion of 10min, the patient cheek flushing, followed by swelling of the eyelids, facial rashes, pressure of the fade. Children with abdominal discomfort, but the limbs and torso were no rash, heart rate 90 beats / min, law Qi, abdominal soft, bowel sounds normal, history, history has been 2 times, did not pay attention to consider with penicillin Allergy, immediately disable penicillin, exchange for lincomycin intravenous infusion, about 3h, the children disappeared.