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目的 :探讨九代清源口服液在增强反复呼吸道感染患儿免疫功能中的作用。方法 :将 10 0例RRI患儿随机分为 2组 ,即常规治疗组和九代清源口服液辅助治疗组 (简称九代组 ) ,分别于治疗前、治疗后抽取静脉血检测T淋巴细胞亚群 (SP法 )、NK细胞活性 (MTT法 )、sIL 2R(ELISA法 )、IgG、IgA、IgM(透射比浊法 )。结果 :RRI患儿治疗前CD3+ 、CD4+ 、CD4+ CD8+ 、NK细胞活性及IgG、IgA显著降低 ,CD8+ 、IgM和sIL 6R显著升高常规治疗后各指标明显好转 ,与正常对照组比较 ,仍有显著差异 (P <0 0 5 ) ;九代组治疗后有所恢复 ,但与正常对照组比较均无显著性差异 (P >0 0 5 )。结论 :九代清源口服液具有较强的免疫调节作用 ,可明显增强RRI患儿的细胞和体液免疫功能
Objective: To investigate the role of Jiading Qingyuan oral liquid in enhancing the immune function of children with recurrent respiratory tract infection. Methods: One hundred and ten cases of RRI were randomly divided into two groups: conventional treatment group and Jiuxing Qingyuan oral liquid adjuvant therapy group (referred to as Jiu-Dai group). Venous blood was collected before treatment and after treatment, respectively. T lymphocytes (SP method), NK cell activity (MTT method), sIL 2R (ELISA method), IgG, IgA, IgM (turbidimetric method). Results: The activity of CD3 +, CD4 +, CD4 + CD8 +, NK cells and IgG, IgA, CD8 +, IgM and sIL 6R in RRI children before treatment were significantly higher than those in normal control group (P <0.05). Nine-generation group recovered after treatment, but there was no significant difference compared with the normal control group (P> 0.05). Conclusion: Nine generations of Qingyuan oral liquid has a strong immunomodulatory effect, can significantly enhance the cellular and humoral immune function in children with RRI